KEGG pathway : ko04151

ko04151: PI3K-Akt signaling pathway

Genes annotated with KAAS are mapped onto the ko04151 map with pathview. genes colored in red are conserved in P. vanderplanki.

Orthologs for this pathway

• K00693
  • EC:2.4.1.11: glycogen synthase
  • g11259
• K00922
  • EC:2.7.1.153: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  • g12521
• K01084
  • EC:3.1.3.9: glucose-6-phosphatase
  • g674
• K01110
  • EC:3.1.3.16: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K01110
  • EC:3.1.3.48: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K01110
  • EC:3.1.3.67: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  • g5232
• K01596
  • EC:4.1.1.32: phosphoenolpyruvate carboxykinase (GTP)
  • g14398, g2850
• K02089
  • EC:2.7.11.22: cyclin-dependent kinase 4
  • g8600
• K02091
  • EC:2.7.11.22: cyclin-dependent kinase 6
  • g8600
• K02206
  • EC:2.7.11.22: cyclin-dependent kinase 2
  • g2875
• K02580
  • Other:Other
  • g8884
• K02649
  • Other:Other
  • g8805
• K02677
  • EC:2.7.11.13: classical protein kinase C alpha type
  • g14087
• K02991
  • Other:Other
  • g11474
• K03083
  • EC:2.7.11.26: glycogen synthase kinase 3 beta
  • g10412
• K03099
  • Other:Other
  • g11725
• K03258
  • Other:Other
  • g9263
• K03259
  • Other:Other
  • g7741, g2574
• K03456
  • Other:Other
  • g12696
• K03900
  • Other:Other
  • g5301
• K04079
  • Other:Other
  • g2254
• K04354
  • Other:Other
  • g3683
• K04361
  • EC:2.7.10.1: epidermal growth factor receptor
  • g5568
• K04362
  • EC:2.7.10.1: fibroblast growth factor receptor 1
  • g16687
• K04364
  • Other:Other
  • g3171
• K04368
  • EC:2.7.12.2: mitogen-activated protein kinase kinase 1
  • g2128
• K04371
  • EC:2.7.11.24: mitogen-activated protein kinase 1/3
  • g9093
• K04374
  • Other:Other
  • g14005
• K04377
  • Other:Other
  • g14105
• K04382
  • EC:3.1.3.16: serine/threonine-protein phosphatase 2A catalytic subunit
  • g4259
• K04392
  • Other:Other
  • g359, g9936, g11879
• K04447
  • EC:2.7.10.2: Janus kinase 2
  • g4919
• K04450
  • Other:Other
  • g13032
• K04456
  • EC:2.7.11.1: RAC serine/threonine-protein kinase
  • g11018, g11019
• K04527
  • EC:2.7.10.1: insulin receptor
  • g15131
• K04536
  • Other:Other
  • g10402
• K04539
  • Other:Other
  • g4565
• K04547
  • Other:Other
  • g4453
• K04659
  • Other:Other
  • g15618, g13797
• K04688
  • EC:2.7.11.1: ribosomal protein S6 kinase beta
  • g11364
• K05087
  • EC:2.7.10.1: insulin-like growth factor 1 receptor
  • g16541, g17037
• K05093
  • EC:2.7.10.1: fibroblast growth factor receptor 2
  • g2994
• K05096
  • EC:2.7.10.1: FMS-like tyrosine kinase 1
  • g5752
• K05449
  • Other:Other
  • g15038, g17518, g12506, g15087, g15081, g14042
• K05631
  • Other:Other
  • g2664
• K05635
  • Other:Other
  • g8714
• K05636
  • Other:Other
  • g11395
• K05637
  • Other:Other
  • g5873, g5874
• K05719
  • Other:Other
  • g13034, g12784
• K05725
  • EC:2.7.10.2: focal adhesion kinase 1
  • g5835
• K05855
  • EC:2.7.10.2: spleen tyrosine kinase
  • g17819
• K05870
  • Other:Other
  • g5515
• K06236
  • Other:Other
  • g7037
• K06237
  • Other:Other
  • g5016, g5804, g5012
• K06240
  • Other:Other
  • g7715
• K06248
  • Other:Other
  • g16489
• K06276
  • EC:2.7.11.1: 3-phosphoinositide dependent protein kinase-1
  • g6496, g15989
• K06626
  • Other:Other
  • g5510
• K06630
  • Other:Other
  • g9526
• K06643
  • EC:2.3.2.27: E3 ubiquitin-protein ligase Mdm2
  • g12122
• K07198
  • EC:2.7.11.11: 5’-AMP-activated protein kinase, catalytic alpha subunit
  • g12671
• K07203
  • EC:2.7.11.1: serine/threonine-protein kinase mTOR
  • g13452
• K07204
  • Other:Other
  • g8236
• K07206
  • Other:Other
  • g2022
• K07207
  • Other:Other
  • g9369
• K07208
  • Other:Other
  • g9421
• K07298
  • EC:2.7.11.1: serine/threonine-protein kinase 11
  • g10880
• K07827
  • Other:Other
  • g3228
• K08266
  • Other:Other
  • g17274
• K09048
  • Other:Other
  • g11706, g3849
• K09408
  • Other:Other
  • g363
• K09420
  • Other:Other
  • g12063
• K09487
  • Other:Other
  • g3606
• K09554
  • Other:Other
  • g11456
• K10151
  • Other:Other
  • g12224
• K11583
  • Other:Other
  • g11450
• K11584
  • Other:Other
  • g11729, g2965
• K13303
  • EC:2.7.11.1: serum/glucocorticoid-regulated kinase 2
  • g11018
• K16172
  • Other:Other
  • g4456
• K16197
  • Other:Other
  • g10748
• K16340
  • EC:3.1.3.16: PH domain and leucine-rich repeat-containing protein phosphatase
  • g5727
• K19719
  • Other:Other
  • g7039
• K23691
  • EC:2.7.11.13: serine/threonine-protein kinase N2
  • g8641