KEGG pathway : ko05022

ko05022: Pathways of neurodegeneration - multiple diseases

Genes annotated with KAAS are mapped onto the ko05022 map with pathview. genes colored in red are conserved in P. vanderplanki.

Orthologs for this pathway

• K00234
  • EC:1.3.5.1: succinate dehydrogenase (ubiquinone) flavoprotein subunit
  • g2209
• K00235
  • EC:1.3.5.1: succinate dehydrogenase (ubiquinone) iron-sulfur subunit
  • g7717
• K00236
  • Other:Other
  • g703, g17494
• K00237
  • Other:Other
  • g2694
• K00411
  • EC:7.1.1.8: ubiquinol-cytochrome c reductase iron-sulfur subunit
  • g6000
• K00413
  • Other:Other
  • g8234
• K00415
  • Other:Other
  • g6959
• K00416
  • Other:Other
  • g3994
• K00417
  • Other:Other
  • g3322
• K00418
  • Other:Other
  • g3856
• K00432
  • EC:1.11.1.9: glutathione peroxidase
  • g13509, g13511
• K00444
  • Other:Other
  • g10660
• K00445
  • Other:Other
  • g5740
• K00572
  • Other:Other
  • g10654
• K00914
  • EC:2.7.1.137: phosphatidylinositol 3-kinase
  • g11722
• K01116
  • EC:3.1.4.11: phosphatidylinositol phospholipase C, gamma-1
  • g10026
• K01357
  • Other:Other
  • g5739
• K02084
  • Other:Other
  • g10452
• K02085
  • Other:Other
  • g7851
• K02090
  • EC:2.7.11.22: cyclin-dependent kinase 5
  • g14860
• K02105
  • Other:Other
  • g13374
• K02127
  • Other:Other
  • g5732
• K02128
  • Other:Other
  • g9266
• K02131
  • Other:Other
  • g2903
• K02132
  • Other:Other
  • g1669
• K02133
  • EC:7.1.2.2: F-type H+-transporting ATPase subunit beta
  • g7327
• K02134
  • Other:Other
  • g10613
• K02136
  • Other:Other
  • g12122
• K02137
  • Other:Other
  • g10803
• K02138
  • Other:Other
  • g2383
• K02157
  • Other:Other
  • g10580
• K02183
  • Other:Other
  • g10355, g11432
• K02263
  • Other:Other
  • g12311
• K02264
  • Other:Other
  • g10841
• K02265
  • Other:Other
  • g13857
• K02266
  • Other:Other
  • g8637
• K02267
  • Other:Other
  • g3984
• K02270
  • Other:Other
  • g370
• K02353
  • Other:Other
  • g2662
• K02354
  • Other:Other
  • g5559
• K02375
  • Other:Other
  • g12545
• K02432
  • Other:Other
  • g7854
• K02580
  • Other:Other
  • g8884
• K02677
  • EC:2.7.11.13: classical protein kinase C alpha type
  • g14087
• K02725
  • EC:3.4.25.1: 20S proteasome subunit alpha 6
  • g13361
• K02726
  • EC:3.4.25.1: 20S proteasome subunit alpha 2
  • g5793
• K02727
  • EC:3.4.25.1: 20S proteasome subunit alpha 7
  • g11495
• K02728
  • EC:3.4.25.1: 20S proteasome subunit alpha 3
  • g4076
• K02729
  • EC:3.4.25.1: 20S proteasome subunit alpha 5
  • g5573
• K02730
  • EC:3.4.25.1: 20S proteasome subunit alpha 1
  • g8196
• K02731
  • EC:3.4.25.1: 20S proteasome subunit alpha 4
  • g13240
• K02732
  • EC:3.4.25.1: 20S proteasome subunit beta 6
  • g7711
• K02734
  • EC:3.4.25.1: 20S proteasome subunit beta 4
  • g4362
• K02735
  • EC:3.4.25.1: 20S proteasome subunit beta 3
  • g11646
• K02736
  • EC:3.4.25.1: 20S proteasome subunit beta 7
  • g7764
• K02737
  • EC:3.4.25.1: 20S proteasome subunit beta 5
  • g11293
• K02738
  • EC:3.4.25.1: 20S proteasome subunit beta 1
  • g7161
• K02739
  • EC:3.4.25.1: 20S proteasome subunit beta 2
  • g8087, g4781
• K02927
  • Other:Other
  • g11385
• K02977
  • Other:Other
  • g11608
• K03028
  • Other:Other
  • g3380
• K03029
  • Other:Other
  • g12937
• K03030
  • Other:Other
  • g5384
• K03031
  • Other:Other
  • g6180
• K03032
  • Other:Other
  • g10380
• K03033
  • Other:Other
  • g4920
• K03035
  • Other:Other
  • g3360
• K03036
  • Other:Other
  • g446
• K03037
  • Other:Other
  • g805
• K03038
  • Other:Other
  • g3693
• K03039
  • Other:Other
  • g936
• K03061
  • Other:Other
  • g9569
• K03062
  • Other:Other
  • g1602
• K03063
  • Other:Other
  • g11790
• K03064
  • Other:Other
  • g6491
• K03065
  • Other:Other
  • g2793
• K03066
  • Other:Other
  • g7951
• K03068
  • Other:Other
  • g2360
• K03083
  • EC:2.7.11.26: glycogen synthase kinase 3 beta
  • g10412
• K03097
  • EC:2.7.11.1: casein kinase II subunit alpha
  • g10340
• K03115
  • Other:Other
  • g3844
• K03178
  • EC:6.2.1.45: ubiquitin-activating enzyme E1
  • g3898
• K03209
  • Other:Other
  • g5742
• K03237
  • Other:Other
  • g7321
• K03781
  • EC:1.11.1.6: catalase
  • g7294
• K03934
  • EC:7.1.1.2: NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • g9926
• K03935
  • EC:7.1.1.2: NADH dehydrogenase (ubiquinone) Fe-S protein 2
  • g13993
• K03936
  • EC:7.1.1.2: NADH dehydrogenase (ubiquinone) Fe-S protein 3
  • g9732
• K03937
  • Other:Other
  • g3731
• K03938
  • Other:Other
  • g5681
• K03939
  • Other:Other
  • g6097
• K03940
  • EC:7.1.1.2: NADH dehydrogenase (ubiquinone) Fe-S protein 7
  • g12171
• K03941
  • EC:7.1.1.2: NADH dehydrogenase (ubiquinone) Fe-S protein 8
  • g12443
• K03942
  • EC:7.1.1.2: NADH dehydrogenase (ubiquinone) flavoprotein 1
  • g5428
• K03943
  • EC:7.1.1.2: NADH dehydrogenase (ubiquinone) flavoprotein 2
  • g3938
• K03945
  • Other:Other
  • g7108
• K03946
  • Other:Other
  • g11696
• K03948
  • Other:Other
  • g2876
• K03949
  • Other:Other
  • g4840
• K03950
  • Other:Other
  • g9884
• K03951
  • Other:Other
  • g9995
• K03952
  • Other:Other
  • g733
• K03953
  • Other:Other
  • g2394
• K03954
  • Other:Other
  • g11558
• K03955
  • Other:Other
  • g16826, g9302
• K03956
  • Other:Other
  • g8609
• K03958
  • Other:Other
  • g4119
• K03959
  • Other:Other
  • g3580
• K03960
  • Other:Other
  • g11124
• K03961
  • Other:Other
  • g7157
• K03962
  • Other:Other
  • g5509
• K03963
  • Other:Other
  • g615
• K03964
  • Other:Other
  • g6742
• K03965
  • Other:Other
  • g10689
• K03966
  • Other:Other
  • g4921
• K03968
  • Other:Other
  • g3820
• K04131
  • Other:Other
  • g10239, g3110
• K04348
  • EC:3.1.3.16: serine/threonine-protein phosphatase 2B catalytic subunit
  • g1333
• K04365
  • EC:2.7.11.1: B-Raf proto-oncogene serine/threonine-protein kinase
  • g8869
• K04368
  • EC:2.7.12.2: mitogen-activated protein kinase kinase 1
  • g2128
• K04371
  • EC:2.7.11.24: mitogen-activated protein kinase 1/3
  • g9093
• K04374
  • Other:Other
  • g14005
• K04380
  • Other:Other
  • g358
• K04385
  • Other:Other
  • g10580
• K04392
  • Other:Other
  • g359, g9936, g11879
• K04397
  • EC:3.4.22.60: caspase 7
  • g418, g13464
• K04398
  • EC:3.4.22.61: caspase 8
  • g1229
• K04426
  • EC:2.7.11.25: mitogen-activated protein kinase kinase kinase 5
  • g8333
• K04431
  • EC:2.7.12.2: mitogen-activated protein kinase kinase 7
  • g8567
• K04432
  • EC:2.7.12.2: mitogen-activated protein kinase kinase 3
  • g12056
• K04440
  • EC:2.7.11.24: mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  • g13104
• K04441
  • EC:2.7.11.24: p38 MAP kinase
  • g10681
• K04505
  • Other:Other
  • g16954
• K04515
  • EC:2.7.11.17: calcium/calmodulin-dependent protein kinase (CaM kinase) II
  • g2644, g9676
• K04520
  • Other:Other
  • g3809
• K04533
  • Other:Other
  • g17448
• K04551
  • Other:Other
  • g4090
• K04552
  • EC:2.3.2.23: ubiquitin-conjugating enzyme E2 L3
  • g3123
• K04554
  • EC:2.3.2.23: ubiquitin-conjugating enzyme E2 J2
  • g11305
• K04555
  • EC:2.3.2.23: ubiquitin-conjugating enzyme E2 G2
  • g3367
• K04556
  • EC:2.3.2.31: parkin
  • g14285
• K04559
  • Other:Other
  • g15259
• K04560
  • Other:Other
  • g959
• K04565
  • EC:1.15.1.1: superoxide dismutase, Cu-Zn family
  • g7534, g8507, g16289, g16280, g13490
• K04569
  • Other:Other
  • g4810
• K04575
  • Other:Other
  • g15760
• K04603
  • Other:Other
  • g13542
• K04634
  • Other:Other
  • g6985
• K04638
  • Other:Other
  • g4567
• K04648
  • Other:Other
  • g7317
• K04690
  • Other:Other
  • g12986
• K04809
  • Other:Other
  • g13491
• K04851
  • Other:Other
  • g16833
• K04958
  • Other:Other
  • g14909, g14904
• K04962
  • Other:Other
  • g11391
• K05036
  • Other:Other
  • g6898
• K05208
  • Other:Other
  • g2415
• K05210
  • Other:Other
  • g14132
• K05410
  • EC:2.7.11.10: TANK-binding kinase 1
  • g8847
• K05687
  • EC:3.5.1.124: protein DJ-1
  • g9606
• K05853
  • EC:7.2.2.10: P-type Ca2+ transporter type 2A
  • g3059
• K05858
  • EC:3.1.4.11: phosphatidylinositol phospholipase C, beta
  • g9592, g5962
• K05863
  • Other:Other
  • g6957
• K05864
  • EC:5.2.1.8: peptidyl-prolyl isomerase D
  • g9331
• K06030
  • Other:Other
  • g10209
• K06268
  • Other:Other
  • g16318, g8138
• K06691
  • Other:Other
  • g2060
• K06693
  • Other:Other
  • g1155
• K07203
  • EC:2.7.11.1: serine/threonine-protein kinase mTOR
  • g13452
• K07374
  • Other:Other
  • g14768, g2687
• K07375
  • Other:Other
  • g13912, g13965, g134, g5213, g13911, g5214
• K07827
  • Other:Other
  • g3228
• K07874
  • Other:Other
  • g13663, g1674
• K07901
  • Other:Other
  • g11563
• K07925
  • Other:Other
  • g13385
• K08269
  • EC:2.7.11.1: serine/threonine-protein kinase ULK2
  • g1322
• K08331
  • Other:Other
  • g7946
• K08333
  • EC:2.7.11.1: phosphoinositide-3-kinase, regulatory subunit 4
  • g1502
• K08334
  • Other:Other
  • g14121
• K08669
  • EC:3.4.21.108: HtrA serine peptidase 2
  • g1595
• K08683
  • EC:1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • g332
• K08683
  • EC:1.1.1.178: 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • g332
• K08738
  • Other:Other
  • g8774, g4467
• K08770
  • Other:Other
  • g4090
• K08852
  • Other:Other
  • g16433, g6124
• K08860
  • EC:2.7.11.1: eukaryotic translation initiation factor 2-alpha kinase 3
  • g9617
• K08957
  • EC:2.7.11.1: casein kinase 1, alpha
  • g13984
• K08960
  • EC:2.7.11.1: casein kinase 1, epsilon
  • g7361
• K09027
  • Other:Other
  • g8208
• K09054
  • Other:Other
  • g7766
• K09488
  • Other:Other
  • g14417
• K09490
  • EC:3.6.4.10: endoplasmic reticulum chaperone BiP
  • g2685
• K09565
  • EC:5.2.1.8: peptidyl-prolyl isomerase F (cyclophilin D)
  • g10620
• K10396
  • Other:Other
  • g12301
• K10407
  • Other:Other
  • g11349
• K10408
  • Other:Other
  • g5058, g9449, g10500, g5598, g11748, g11354, g12248, g1029, g6319
• K10409
  • Other:Other
  • g12335
• K10410
  • Other:Other
  • g2802
• K10411
  • Other:Other
  • g15852
• K10412
  • Other:Other
  • g7841
• K10424
  • Other:Other
  • g8359
• K10425
  • Other:Other
  • g2313
• K10426
  • Other:Other
  • g3382
• K10427
  • Other:Other
  • g8970
• K10428
  • Other:Other
  • g1139
• K10575
  • EC:2.3.2.23: ubiquitin-conjugating enzyme E2 G1
  • g9156, g9154
• K10707
  • Other:Other
  • g12499
• K11143
  • Other:Other
  • g1531
• K11351
  • Other:Other
  • g8218
• K11352
  • Other:Other
  • g6065
• K11353
  • Other:Other
  • g4869
• K11518
  • Other:Other
  • g7299
• K11519
  • Other:Other
  • g6545
• K11716
  • Other:Other
  • g13573
• K11828
  • Other:Other
  • g13718
• K13098
  • Other:Other
  • g618
• K13240
  • EC:1.14.13.39: nitric-oxide synthase, brain
  • g6966
• K13525
  • Other:Other
  • g9940
• K15040
  • Other:Other
  • g4858
• K16575
  • Other:Other
  • g9607
• K16576
  • Other:Other
  • g4079
• K17589
  • Other:Other
  • g13728
• K17603
  • Other:Other
  • g7853
• K17889
  • Other:Other
  • g10325
• K17906
  • Other:Other
  • g8130
• K17908
  • Other:Other
  • g9530, g12284
• K19026
  • Other:Other
  • g15887
• K19730
  • Other:Other
  • g14026
• K20858
  • Other:Other
  • g7302
• K22913
  • Other:Other
  • g4615
• K23600
  • Other:Other
  • g10965
• K23616
  • Other:Other
  • g12179
• K23625
  • Other:Other
  • g10039